Gloria Reuben (born June 9, 1964 in Toronto) is a Canadian actress of film and television, best known for her role on ER.Her Jamaican mother was a gospel singer. She is a biracial Jamaican Canadian. She began learning piano as a child and studied later music technique and theory, ballet and jazz at the Canadian Royal Conservatory.

Her career as an actress was triggered by a few jobs as model and TV ad appearances.She is best known for her role as Jeanie Boulet, a worker in the hospital infected with HIV. She was a guest star throughout season 1 on ER and was elevated to full time cast member towards the end of season 2.

She continued that role until early season 6, when she departed the show.In 2000 she sang back up for Tina Turner on her Twenty Four Seven Tour.In 1996 she was chosen by People as one of the 50 most beautiful people in the world.

Reuben is the sister of Denis Simpson, an actor and children's television host.